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1.
ABC., imagem cardiovasc ; 36(1): e20230006, abr. 2023. ilus, tab
Artigo em Português | LILACS | ID: biblio-1517806

RESUMO

A regurgitação tricúspide (RT) importante está associada à alta morbidade e mortalidade. Como o tratamento cirúrgico da RT isolada tem sido associado à alta mortalidade, as intervenções transcateter na valva tricúspide (VT) têm sido utilizadas para o seu tratamento, com risco relativamente mais baixo. Há um atraso na intervenção da RT e provavelmente está relacionado a uma compreensão limitada da anatomia da VT e do ventrículo direito, além da subestimação da gravidade da RT. Nesse cenário, faz-se necessário o conhecimento anatômico abrangente da VT, a fisiopatologia envolvida no mecanismo de regurgitação, assim como a sua graduação mais precisa. A VT tem peculiaridades anatômica, histológica e espacial que fazem a sua avalição ser mais complexa, quando comparado à valva mitral, sendo necessário o conhecimento e treinamento nas diversas técnicas ecocardiográficas que serão utilizadas frequentemente em combinação para uma avaliação precisa. Esta revisão descreverá a anatomia da VT, o papel do ecocardiograma no diagnóstico, graduação e fisiopatologia envolvida na RT, as principais opções atuais de tratamento transcateter da RT e a avaliação do resultado após intervenção transcateter por meio de múltiplas modalidades ecocardiográficas.(AU)


Severe tricuspid regurgitation (TR) is associated with high morbidity and mortality. Given that surgical treatment of TR alone has been associated with high mortality, transcatheter interventions in the tricuspid valve (TV) have been used for its treatment, with relatively lower risk. There is a delay in intervention for TR, and this is probably related to a limited understanding of the anatomy of the TV and the right ventricle, in addition to an underestimation of the severity of TR. In this scenario, it is necessary to have comprehensive anatomical knowledge of the TV, the pathophysiology involved in the mechanism of regurgitation, and more accurate grading. The TV has anatomical, histological, and spatial peculiarities that make its assessment more complex when compared to the mitral valve, requiring knowledge and training in the various echocardiographic techniques that will often be used in combination for accurate assessment. This review will describe the anatomy of the TV, the role of echocardiography in the diagnosis, grading, and pathophysiology involved in TR; the main transcatheter treatment options currently available for TR; and the assessment of outcomes after transcatheter intervention by means of multiple echocardiographic modalities.(AU)


Assuntos
Humanos , Masculino , Feminino , Valva Tricúspide/anatomia & histologia , Insuficiência da Valva Tricúspide/cirurgia , Insuficiência da Valva Tricúspide/fisiopatologia , Derrame Pericárdico/complicações , Insuficiência da Valva Tricúspide/mortalidade , Ecocardiografia/métodos , Ecocardiografia Transesofagiana/métodos , Ecocardiografia Doppler em Cores/métodos , Ecocardiografia Tridimensional/métodos , Endocardite/complicações , Substituição da Valva Aórtica Transcateter/métodos
3.
ABC., imagem cardiovasc ; 35(1): eabc245, 2022. ilus, tab
Artigo em Português | LILACS | ID: biblio-1369683

RESUMO

Introdução: A excursão sistólica do anel tricúspide e a do anel mitral são parâmetros utilizados para se avaliar a função contrátil do ventrículo direito e do ventrículo esquerdo, respectivamente. Pouco se conhece sobre sua relação com a função diastólica ventricular esquerda. Objetivo: Avaliar se os valores de excursão sistólica do anel tricúspide e do anel mitral se correlacionam com parâmetros utilizados na avaliação da função diastólica ventricular esquerda. Métodos: Estudo observacional transversal. Foram selecionados 219 indivíduos, sendo 116 mulheres, com função sistólica preservada de ambos os ventrículos. As análises foram feitas separadamente para os sexos masculino e feminino, por meio dos coeficientes de correlação de Pearson e de Sperman. Foram obtidos: excursão sistólica do anel tricúspide, excursão sistólica do anel mitral, volumes atriais e medidas relacionadas à avaliação da função diastólica do ventrículo esquerdo ao ecocardiograma transtorácico. Resultados: No sexo feminino, a excursão sistólica do anel mitral se correlacionou positivamente com o e' lateral (coeficiente de correlação de Sperman de 0,22; p=0,016) e a excursão sistólica do anel tricúspide se correlacionou positivamente com a relação E/A (coeficiente de correlação de Sperman de 0,23, p=0,037), com o e' lateral (coeficiente de correlação de Sperman de 0,28; p=0,012), com o e' septal (coeficiente de correlação de Sperman de 0,28; p=0,012) e negativamente com a relação E/e' (coeficiente de correlação de Pearson de -0,27; p=0,018) e onda A (coeficiente de correlação de Pearson de -0,29; p= 0,009). No sexo masculino, apenas a excursão sistólica do anel mitral se correlacionou positivamente com a onda E (coeficiente de correlação de Pearson de 0,21; p=0,037), e' lateral (coeficiente de correlação de Sperman de 0,34; p <0,001) e e' septal (coeficiente de correlação de Sperman de 0,26; p=0,008). Não houve correlação entre excursão sistólica do anel mitral e do anel tricúspide e volumes atriais. A presença de hipertensão arterial sistêmica e diabetes melito influenciou nos valores de excursão sistólica do anel tricúspide e do anel mitral correlacionados a ondas E e A, relação E/A, ondas e' septal e lateral e relação E/e'. Conclusão: No presente estudo, os valores da excursão sistólica do anel mitral e do anel tricúspide apresentaram correlação significativa com algumas variáveis da função diastólica ventricular esquerda com maior evidência no sexo feminino.(AU)


Introduction: Tricuspid annular plane systolic excursion and mitral annular systolic excursion are parameters used to assess the systolic function of the right ventricle and left ventricle, respectively. Little is known about its relationship with left ventricular diastolic function. Objective: To assess whether the values of mitral annular systolic excursion and tricuspid annular plane systolic excursion correlate with parameters used in the evaluation of left ventricular diastolic function. Method: Observational cross-sectional study. Two hundred nine individuals were selected, 116 women, with both ventricles normal systolic function. The analyzes were performed for men and women, through Pearson correlation coefficient and Sperman correlation coefficient. Tricuspid annular plane systolic excursion, mitral annular systolic excursion, atrial volumes and left ventricular diastolic function parameters on transthoracic echocardiogram were obtained. Results: In women, mitral annular systolic excursion was positively correlated with lateral e '(Sperman correlation coefficient of 0.22; p=0.016) and tricuspid annular plane systolic excursion was positively correlated with E / A ratio (Sperman correlation coefficient of 0.23; p=0.037), lateral e' (Sperman correlation coefficient of 0.28; p=0.012), and septal e' (Sperman correlation coefficient of 0.28; p=0.012), and negatively with the E/e' ratio (Pearson correlation coefficient of -0.27; p=0.018), and A wave (Pearson correlation coefficient of -0.29; p=0.009). In men, only mitral annular systolic excursion correlated positively with E wave (Pearson correlation coefficient of 0.21; p=0.037), lateral e' (Sperman correlation coefficient of 0.34; p <0.001) and the septal e' (Sperman correlation coefficient of 0.26; p=0.008). There was no correlation between mitral annular systolic excursion E and tricuspid annular plane systolic excursion and atrial volumes. Hypertension and diabetes mellitus influenced tricuspid annular plane systolic excursion and mitral annular systolic excursion values correlated to E and A waves, E/A ratio, septal and lateral e' waves, and E/e' ratio. Conclusion: In the present study, mitral annular systolic excursion and tricuspid annular plane systolic excursion values showed a significant correlation with some parameters of left ventricular diastolic function, with stronger evidence on female sex.(AU)


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Valva Tricúspide/anatomia & histologia , Função Ventricular Esquerda/fisiologia , Disfunção Ventricular Esquerda/complicações , Valva Mitral/anatomia & histologia , Ecocardiografia/métodos , Disfunção Ventricular Esquerda/diagnóstico por imagem , Diabetes Mellitus/etiologia , Ventrículos do Coração/fisiopatologia , Hipertensão/complicações
4.
G Ital Cardiol (Rome) ; 21(11): 865-877, 2020 Nov.
Artigo em Italiano | MEDLINE | ID: mdl-33077993

RESUMO

Although the indications for surgical management of severe functional tricuspid regurgitation (TR) are now generally accepted, controversy persists concerning the role of intervention for moderate TR. However, there is a trend for intervention in this setting, particularly in patients with annular dilation. Echocardiographic imaging is the gold standard to identify functional TR and distinguish it from a primitive or degenerative form. Currently, surgery remains the best approach for the interventional treatment of TR. Ring annuloplasty seems to provide better results than suture annuloplasty (De Vega technique) and rigid rings appear to be more reliable in the long term, in comparison with flexible bands. Tricuspid valve repair is more beneficial compared with replacement, except in highly selected cases of long-standing TR with multifactorial mechanism.


Assuntos
Insuficiência da Valva Tricúspide/diagnóstico por imagem , Insuficiência da Valva Tricúspide/cirurgia , Valva Tricúspide/cirurgia , Ecocardiografia/normas , Implante de Prótese de Valva Cardíaca , Humanos , Imageamento por Ressonância Magnética , Resultado do Tratamento , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/diagnóstico por imagem , Valva Tricúspide/fisiopatologia , Insuficiência da Valva Tricúspide/etiologia , Insuficiência da Valva Tricúspide/fisiopatologia
5.
Int J Mol Sci ; 21(18)2020 Sep 05.
Artigo em Inglês | MEDLINE | ID: mdl-32899559

RESUMO

Surgical simulators and injury-prediction human models require a combination of representative tissue geometry and accurate tissue material properties to predict realistic tool-tissue interaction forces and injury mechanisms, respectively. While biological tissues have been individually characterized, the transition regions between tissues have received limited research attention, potentially resulting in inaccuracies within simulations. In this work, an approach to characterize the transition regions in transversely isotropic (TI) soft tissues using functionally graded material (FGM) modeling is presented. The effect of nonlinearities and multi-regime nature of the TI model on the functional grading process is discussed. The proposed approach has been implemented to characterize the transition regions in the leaflet (LL), chordae tendinae (CT) and the papillary muscle (PM) of porcine tricuspid valve (TV) and mitral valve (MV). The FGM model is informed using high resolution morphological measurements of the collagen fiber orientation and tissue composition in the transition regions, and deformation characteristics predicted by the FGM model are numerically validated to experimental data using X-ray diffraction imaging. The results indicate feasibility of using the FGM approach in modeling soft-tissue transitions and has implications in improving physical representation of tissue deformation throughout the body using a scalable version of the proposed approach.


Assuntos
Valva Mitral/fisiologia , Valva Tricúspide/fisiologia , Difração de Raios X/métodos , Animais , Fenômenos Biomecânicos , Cordas Tendinosas/fisiologia , Simulação por Computador , Análise de Elementos Finitos , Valva Mitral/anatomia & histologia , Modelos Biológicos , Modelos Cardiovasculares , Modelos Teóricos , Músculos Papilares/fisiologia , Estresse Mecânico , Suínos , Valva Tricúspide/anatomia & histologia
6.
J Card Surg ; 35(11): 3138-3140, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32789873

RESUMO

Patients with congenital heart disease are surviving well into adulthood thanks to advances in medical and clinical care. We present a patient with Ebstein anomaly who underwent surgical tricuspid valve replacement and suffered early valve stenosis due to her unique anatomy. This case highlights the importance of the "unnatural" anatomy that can be encounter in this challenging patient population.


Assuntos
Variação Anatômica , Bioprótese/efeitos adversos , Anomalia de Ebstein/cirurgia , Implante de Prótese de Valva Cardíaca/efeitos adversos , Implante de Prótese de Valva Cardíaca/métodos , Desenho de Prótese/efeitos adversos , Estenose da Valva Tricúspide/etiologia , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/cirurgia , Anomalia de Ebstein/complicações , Feminino , Comunicação Interatrial/complicações , Comunicação Interatrial/cirurgia , Humanos , Pessoa de Meia-Idade , Resultado do Tratamento
7.
J Ultrasound Med ; 39(5): 929-937, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31737932

RESUMO

OBJECTIVES: The aim of this study was to construct reference ranges for fetal tricuspid annular plane systolic excursion (TAPSE) and mitral annular plane systolic excursion (MAPSE) using conventional M-mode ultrasound (US) in the second half of pregnancy. METHODS: Participants underwent US scans every 4 weeks from 18 weeks' gestation until delivery. The TAPSE and MAPSE were measured by conventional M-mode US at each examination. The relationships between TAPSE and MAPSE and gestational age and estimated fetal weight were modeled by Bayesian mixed effects linear regression. RESULTS: Positive linear relationships were observed between both MAPSE and TAPSE and gestational age and estimated fetal weight. Reference centiles for TAPSE and MAPSE were developed. CONCLUSIONS: This simple technique is a useful tool for assessing cardiac function and could be used for quantitative assessments of fetal cardiac function, particularly in high-risk pregnancies such as those complicated by maternal diabetes.


Assuntos
Ecocardiografia/métodos , Valva Mitral/anatomia & histologia , Valva Mitral/embriologia , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/embriologia , Ultrassonografia Pré-Natal/métodos , Adulto , Austrália , Teorema de Bayes , Feminino , Humanos , Estudos Longitudinais , Gravidez , Estudos Prospectivos , Valores de Referência
8.
ABC., imagem cardiovasc ; 33(1): [e000AO32], 2020.
Artigo em Português | LILACS | ID: biblio-1052460

RESUMO

Introdução: A avaliação sistemática das dimensões e da função das câmaras direitas, de acordo com sexo, idade, superfície corporal e índice de massa corporal, não é uniformemente realizada. Objetivo: Avaliar, ao ecocardiograma transtorácico, as dimensões e a função das câmaras direitas de acordo com o sexo, superfície corporal e índice de massa corporal em uma população ambulatorial. Métodos: Estudo observacional, transversal. Foram selecionados 81 pacientes, 60,4 ± 13,5 anos, de ambos os sexos (57 mulheres, 70%). Foram avaliados: diâmetro proximal do ventrículo direito, basal do ventrículo direito, médio e longitudinal; área do átrio direito e volume do átrio direito; espessura da parede livre do ventrículo direito; excursão sistólica do anel valvar tricúspide; e Doppler tecidual do anel tricúspide, onda S'. Resultados: O sexo feminino apresentou menores diâmetros em relação ao sexo masculino (teste t de Student) de diâmetro proximal do ventrículo direito (20,6 mm ± 2,4 vs. 22,7 mm ± 2,2; p = 0,001), basal do ventrículo direito (34,4 mm ± 3,5 vs. 38,2 mm ± 4,8; p < 0,001), diâmetro médio do ventrículo direito (27 mm ± 3,3 vs. 32,4 mm ± 4,9; p < 0,001), área do átrio direito (13,7 cm² ± 2,7 vs. 16,6 cm² ± 3,9; p = 0,002) e volume do átrio direito (37 mL ± 10,6 vs. 50,7 mL ± 15,6 ; p = 0,002). O índice de massa corporal e a superfície corporal se correlacionaram positivamente com o diâmetro proximal do ventrículo direito (coeficiente de correlação - CC 0,24; p = 0,03), diâmetro basal do ventrículo direito (CC 0,22; p = 0,04), diâmetro médio do ventrículo direito (CC 0,23; p = 0,04), diâmetro longitudinal do ventrículo direito (CC 0,28; p = 0,01), área do átrio direito (CC 0,40; p = 0,001) e volume do átrio direito (CC 0,24; p = 0,0006). Conclusão: As médias dos diâmetros ventriculares, área e volume atriais direitos foram menores no sexo feminino. Foi encontrada correlação positiva destes parâmetros com o índice de massa corporal e a superfície corporal. Os valores da excursão sistólica do anel valvar tricúspide e S' não foram influenciados por sexo, índice de massa corporal e superfície corporal.


Introduction: Assessment of right chambers dimensions and function according to gender, age, body surface area and body mass index is not uniformly performed. Objective: To evaluate, by transthoracic echocardiography dimensions and function of right chambers, according to gender, body surface area and body mass index in an outpatient population. Method: Cross-sectional study. Eighty-one patients were selected, 60.4 ± 13.5 years (57 women, 70%). Parameters assessed were the following: proximal, basal, medium and longitudinal, right ventricle diameter; right atrium area and right atrium volume; right ventricle wall thickness; tricuspid annular plane systolic excursion; and tricuspid annulus tissue Doppler and S' wave. Results: Female sex presented lower diameters (Student's t-test) of proximal right ventricle diameter (20.6 mm ± 2.4 vs. 22.7 mm ± 2.2; p = 0.001), basal right ventricle diameter (34,4 mm ± 3,5 vs. 38,2 mm ± 4,8; p <0.001), medium right ventricle diameter (27 mm ± 3.3 vs. 32.4 mm ± 4.9; p <0.001), right atrium area (13.7 cm² ± 2.7 vs. 16.6 cm² ± 3.9; p = 0.002) and right atrium volume (37 mL ± 10.6 vs.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Adulto Jovem , Valva Tricúspide/anatomia & histologia , Átrios do Coração/anatomia & histologia , Ventrículos do Coração/anatomia & histologia , Superfície Corporal , Ecocardiografia , Índice de Massa Corporal , Fatores Sexuais , Estudos Transversais
9.
Prog Cardiovasc Dis ; 62(6): 459-462, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31801699

RESUMO

The rapid development of transcatheter tricuspid valve intervention (TTVI) therapies has quickly provided the opportunity to improve patient selection and procedural planning for patients with significant tricuspid regurgitation (TR) considered at high surgical risk. This review focuses on the contributions which both computed tomography angiography and cardiac magnetic resonance can provide in the better understanding of the natural history of TR, in the comprehensive anatomical and functional assessment of right heart involvement and in the timing and planning for TTVI. We also discuss areas of potential importance such as the quantification of response to TTVI, which will be informative for future trials.


Assuntos
Angiografia por Tomografia Computadorizada , Implante de Prótese de Valva Cardíaca/métodos , Imageamento por Ressonância Magnética , Insuficiência da Valva Tricúspide , Valva Tricúspide , Cateterismo Cardíaco/métodos , Angiografia por Tomografia Computadorizada/métodos , Angiografia por Tomografia Computadorizada/tendências , Humanos , Imageamento por Ressonância Magnética/métodos , Imageamento por Ressonância Magnética/tendências , Seleção de Pacientes , Tempo para o Tratamento , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/diagnóstico por imagem , Valva Tricúspide/fisiopatologia , Insuficiência da Valva Tricúspide/diagnóstico , Insuficiência da Valva Tricúspide/cirurgia
11.
Prog Cardiovasc Dis ; 62(6): 452-458, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31669497

RESUMO

Echocardiographic imaging is an integral part of characterizing patients with tricuspid regurgitation (TR) and helps in determining the timing of intervention and procedural guidance for transcatheter interventions. The rapid advances in both two-dimensional and three-dimensional imaging however have facilitated the development and deployment of novel transcatheter devices to address the unmet need for patients with symptomatic severe TR.


Assuntos
Cateterismo Cardíaco/métodos , Ecocardiografia/métodos , Implante de Prótese de Valva Cardíaca , Insuficiência da Valva Tricúspide , Valva Tricúspide , Implante de Prótese de Valva Cardíaca/instrumentação , Implante de Prótese de Valva Cardíaca/métodos , Humanos , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/diagnóstico por imagem , Valva Tricúspide/cirurgia , Insuficiência da Valva Tricúspide/diagnóstico , Insuficiência da Valva Tricúspide/cirurgia
12.
Prog Cardiovasc Dis ; 62(6): 488-492, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31655080

RESUMO

Transcatheter therapy with the MitraClip system (Abbott Structural, Menlo Park, CA) is the most commonly used transcatheter therapy for patients with tricuspid regurgitation, with over 1000 cases performed worldwide. The procedure is an off-label approach that requires meticulous attention to anatomical features obtained via comprehensive echocardiography and, in some cases, using cardiac computed tomography. Herein, we describe patient selection, procedural performance, and clinical outcomes of this therapy.


Assuntos
Ecocardiografia/métodos , Implante de Prótese de Valva Cardíaca , Próteses Valvulares Cardíacas , Insuficiência da Valva Tricúspide , Valva Tricúspide , Cateterismo Cardíaco/métodos , Desenho de Equipamento , Implante de Prótese de Valva Cardíaca/efeitos adversos , Implante de Prótese de Valva Cardíaca/instrumentação , Implante de Prótese de Valva Cardíaca/métodos , Humanos , Seleção de Pacientes , Índice de Gravidade de Doença , Resultado do Tratamento , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/diagnóstico por imagem , Valva Tricúspide/cirurgia , Insuficiência da Valva Tricúspide/diagnóstico , Insuficiência da Valva Tricúspide/cirurgia
13.
Curr Cardiol Rep ; 21(7): 63, 2019 05 30.
Artigo em Inglês | MEDLINE | ID: mdl-31147795

RESUMO

PURPOSE OF REVIEW: This review discusses the normal anatomy and pathology of the tricuspid valve (TV) and right side of the heart. Emphasis is on those anatomic and pathologic features relevant to interventions intended to restore normal function to the TV in disease states. RECENT FINDINGS: TV pathology is less common than aortic and mitral valve pathology, and treatment and outcomes for interventions face considerable hurdles. New innovations and early data showing safety and efficacy in transcatheter interventions have transformed TV interventions into the next frontier in cardiac valve disease treatment. Certain features of the TV and right heart have presented themselves as potential targets, as well as impediments, for TV intervention. The causes of TV pathology and the anatomy of the TV and right heart bring unique challenges to intervention. Approaches to intervention will continue to progress and change the way we view and treat TV pathology.


Assuntos
Doenças das Valvas Cardíacas/patologia , Insuficiência da Valva Tricúspide/patologia , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/patologia , Implante de Prótese de Valva Cardíaca , Humanos , Resultado do Tratamento , Valva Tricúspide/cirurgia , Insuficiência da Valva Tricúspide/cirurgia
14.
J Anat ; 235(4): 794-802, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31148176

RESUMO

In this work, we studied the structure and function of the adult chicken heart with a focus on the right muscular atrioventricular valve using anatomic and echocardiographic methods. We demonstrated that the free wall thickness of the right and left ventricles changes from the apex to the base of the heart. The right muscular atrioventricular valve (RAVV) is joined directly to both the parietal right ventricle free wall (one attachment) and the interventricular septum (two attachments: ventral and dorsal). This valve does not have chordae tendineae or papillary muscles. The quantitative morphological and functional characterization of the RAVV is given. In color Doppler echo, no regurgitation of blood flow in the RAVV was observed in any of the studied birds. The blood flow velocity in the RAVV is 56.2 ± 9.6 cm s-1 . A contractile function of the RAVV is shown. Based on the findings obtained, we conclude that the RAVV has a sufficient barrier function. In addition, as this valve is an integral part of the right ventricle free wall, it contributes to the right ventricle pump function. An agreed nomenclature of the parts of the RAVV is required.


Assuntos
Galinhas/anatomia & histologia , Galinhas/fisiologia , Ventrículos do Coração/anatomia & histologia , Valva Tricúspide/anatomia & histologia , Função Ventricular/fisiologia , Animais , Valva Tricúspide/fisiologia
15.
Heart Rhythm ; 16(11): 1611-1618, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31150815

RESUMO

BACKGROUND: Radiofrequency (RF) catheter ablation is one of the most common strategies for the current management of cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL). The interindividual anatomic variability can influence the duration and outcome of ablation procedure. OBJECTIVE: The purpose of this study was to establish complication rates in patients undergoing RF catheter ablation for CTI-dependent AFL, assess the role of CTI morphology in procedural success, and determine the anatomic variability of CTI ex vivo. METHODS: RF catheter ablation for CTI-dependent AFL was performed in 337 consecutive patients. Angiographically determined CTI morphology was classified as either simple or complex due to pouchlike recesses. Macroscopic and histologic examination of the CTI was performed in 104 heart specimens from consecutive autopsies. RESULTS: Complex CTI anatomy was present in 10.9% of AFL patients. RF application time to achieve bidirectional isthmus block was longer in patients showing pouchlike recesses than in those without (10.7 vs 8.3 min; P= .025). Acute procedure failure or major complications occurred in 3 cases, all with complex CTI anatomy. A pouchlike recess of the CTI was present in 9.6% of autopsy hearts. Histomorphometric analysis of the CTI atrial wall demonstrated that the central level was the thinnest in the 3 sectors and the paraseptal level was the thickest. CONCLUSION: Although RF catheter ablation is a safe and effective procedure for AFL treatment, CTI anatomic complexity can affect ablation parameters and outcome. Standard definition of CTI morphologic variants is recommended. Preprocedural assessment of CTI anatomy might lead to personalized ablation preventing potential difficulties and complications.


Assuntos
Flutter Atrial/cirurgia , Ablação por Radiofrequência , Valva Tricúspide/anatomia & histologia , Veias Cavas/anatomia & histologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Risco
16.
Am J Cardiol ; 124(4): 594-598, 2019 08 15.
Artigo em Inglês | MEDLINE | ID: mdl-31208699

RESUMO

Tricuspid annular (TA) dilation is a key process in functional tricuspid regurgitation, but normal TA dimensions using cardiovascular magnetic resonance have not been established. We measured TA diameters in 66 healthy volunteers, aged 38 ± 11 years, during 3 different phases of the cardiac cycle (end-systole, early diastole, and end-diastole) and in 2 routinely acquired cardiovascular magnetic resonance imaging planes (4-chamber [4C] and right ventricular inflow-outflow [RVIO]). Three readers independently measured each value and 1 reader repeated measurements 1 month apart. The upper limit of normal (ULN) was calculated as 1.96 standard deviations above the mean. We assessed inter- and intraobserver reliability using the intraclass correlation coefficient (ICC) and Bland-Altman analysis. We found the TA diameter largest during early diastole in the 4C view with an ULN of 43 mm (22 mm/m2). Men had larger absolute TA diameters (36 mm, 95% CI 27 to 44 mm) than women (30 mm, 95% CI 23 to 37 mm) but not after indexing for body surface area (both 18 mm/m2). In the RVIO view, the largest TA diameter occurred during early diastole with a ULN value of 46 mm (27 mm/m2). In this view, females had a larger indexed TA than men (21 mm/m2 vs 17 mm/m2). Reproducibility of measurements was excellent in all cardiac phases with an inter-rater ICC between 0.90 to 0.96 and an intrarater ICC 0.89 to 0.96. In conclusion, we have provided normative data regarding TA dimensions in routinely acquired 4C and RVIO views, and these values are larger than the current thresholds of annular dilation measured by echocardiography. Gender differences with the TA diameter in the RVIO view may be an important finding with consideration of future tricuspid devices.


Assuntos
Imagem Cinética por Ressonância Magnética/métodos , Valva Tricúspide/diagnóstico por imagem , Adulto , Dilatação Patológica/diagnóstico por imagem , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade , Tamanho do Órgão , Valores de Referência , Reprodutibilidade dos Testes , Valva Tricúspide/anatomia & histologia , Insuficiência da Valva Tricúspide/diagnóstico por imagem
17.
Heart Vessels ; 34(10): 1703-1709, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30953137

RESUMO

Cavo-tricuspid isthmus (CTI) anatomies are highly variable, and specific anatomies lead to a difficult CTI ablation. This study aimed to compare the clinical utility of angiography and intracardiac echocardiography (ICE) in evaluating CTI anatomies, and to investigate the impact of the CTI anatomy on the procedure when the ablation tactic was adjusted to the anatomy. This study included 92 consecutive patients who underwent a CTI ablation. The CTI morphology was assessed with both right atrial angiography and ICE before the ablation, and the ablation tactic was adjusted to the anatomy. The mean CTI length was 34 ± 9 mm. On ICE imaging, 21 (23%) patients had a flat CTI, while 41 (45%) had a concave CTI with a mean depth of 5.6 ± 2.7 mm. The remaining 30 (32%) had a distinct pouch with a mean depth of 6.4 ± 2.3 mm, located at the posterior, middle, and anterior isthmus in 15, 14, and 1 patients, respectively. The Eustachian ridge (ER) was visualized in 46 (50%) patients. On angiography, a pouch and ER were detected in 22 and 15 patients, but not in the remaining 8 and 31, respectively. A complete CTI block line was created in all patients without any complications. The CTI anatomy did not significantly impact any procedural parameters. ICE was superior to angiography in evaluating the detailed CTI anatomy, especially pouches and the ER. An adjustment of the ablation tactic to the anatomy could overcome the procedural difficulties of the CTI ablation in cases with specific anatomies.


Assuntos
Angiografia , Fibrilação Atrial/cirurgia , Ablação por Cateter , Ecocardiografia , Sistema de Condução Cardíaco/anatomia & histologia , Sistema de Condução Cardíaco/diagnóstico por imagem , Idoso , Artérias/anatomia & histologia , Artérias/diagnóstico por imagem , Artérias/patologia , Feminino , Átrios do Coração/anatomia & histologia , Átrios do Coração/diagnóstico por imagem , Átrios do Coração/patologia , Sistema de Condução Cardíaco/patologia , Septos Cardíacos/anatomia & histologia , Septos Cardíacos/diagnóstico por imagem , Septos Cardíacos/patologia , Ventrículos do Coração/anatomia & histologia , Ventrículos do Coração/diagnóstico por imagem , Ventrículos do Coração/patologia , Humanos , Cuidados Intraoperatórios , Japão , Masculino , Pessoa de Meia-Idade , Pericárdio/fisiopatologia , Resultado do Tratamento , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/diagnóstico por imagem , Valva Tricúspide/patologia
18.
JAMA Cardiol ; 4(5): 478-487, 2019 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-30994879

RESUMO

Importance: Severe functional or secondary tricuspid regurgitation (TR) is associated with poor long-term outcomes in natural history studies as well as specific disease states. An understanding of the physiologic causes of the TR is lacking precluding a systematic approach to treatment. Observations: The complex anatomic relationship between the tricuspid valve apparatus and structure of the right side of the heart lends insight into the functional changes seen with secondary TR. The association of these changes with changes in pulmonary vascular hemodynamics can lead to a cascade of events that result in disease progression. Conclusions and Relevance: Appreciating the role of pulmonary vascular hemodynamics on right ventricular and tricuspid valve morphology and function improves our understanding of the pathophysiology of secondary TR. The limitations of current therapeutic approaches for secondary TR have stimulated interest in improving outcomes with this morbid disease. Changes in timing or approach to intervention require a more comprehensive understanding of the pathophysiology.


Assuntos
Insuficiência Cardíaca/etiologia , Ventrículos do Coração/anatomia & histologia , Pulmão/fisiologia , Insuficiência da Valva Tricúspide/fisiopatologia , Valva Tricúspide/anatomia & histologia , Progressão da Doença , Ecocardiografia Tridimensional/métodos , Feminino , Insuficiência Cardíaca/epidemiologia , Ventrículos do Coração/diagnóstico por imagem , Hemodinâmica/fisiologia , Humanos , Pulmão/irrigação sanguínea , Masculino , Resultado do Tratamento , Valva Tricúspide/diagnóstico por imagem , Valva Tricúspide/cirurgia , Insuficiência da Valva Tricúspide/complicações
19.
Eur J Cardiothorac Surg ; 56(4): 778-784, 2019 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-30859210

RESUMO

OBJECTIVES: Aortic valve-sparing operations have been shown to produce fewer valve-related complications than valve replacement. The aortic root is a morphological and functional unit in which the annulus plays an important role on dynamism, shape and geometry of the valve with different results in bicuspid aortic valves (BAVs) or tricuspid aortic valves (TAVs). The aim is to evaluate the differences in the size and shape of the aortic annulus between native BAVs and TAVs using ECG-gated computed tomography (CT) after a reimplantation procedure. METHODS: We selected 35 patients scheduled for aortic valve reimplantation who underwent good-quality preoperative and postoperative ECG-gated contrast-enhanced CT scan of the aortic root. Twenty-three patients had TAV, 8 patients type 1 BAV and 4 patients type 0 BAV. Major diameter and minor diameter, perimeter (P) and area (A) were measured. The shape of the aortic annulus was considered 'circular' or 'elliptic' according to the Ellipticity Index. We also selected a subgroup of 18 patients (9 TAVs and 9 BAVs) to evaluate annular shape and size variations through the cardiac cycle and to study the expansibility both in the preoperative and in the postoperative phases. RESULTS: Preoperative CT scans showed an elliptic shape of TAVs (Ellipticity Index 1.3 ± 0.1), a circular shape of type 0 BAVs (1.1 ± 0.1) and an intermediate behaviour of type 1 BAVs, suggesting a possible gradual spectrum of circularity from TAVs to type 1 BAVs to type 0 BAVs. Postoperative CT scans did not show any significant difference in annular shape among the 3 groups, which demonstated a similar roundness, obviating the preoperative differences. Analysing the expansibility of the aortic annulus during the cardiac cycle, we observed that it was completely absent in the preoperative phase in BAVs, while in the postoperative phase, both TAVs and BAVs showed a small but similar expansibility after the annular reduction. CONCLUSIONS: There is a possible gradual spectrum in terms of shape, from native TAVs, to type 1 BAVS to type 0 BAVs. These differences are eliminated in the postoperative phase, suggesting an active role of the annuloplasty on the geometry of the aortic annulus. The preoperative analysis showed a complete inelasticity of BAVs, which was partly restored in the postoperative phase.


Assuntos
Valva Aórtica/anormalidades , Valva Aórtica/cirurgia , Eletrocardiografia , Doenças das Valvas Cardíacas/diagnóstico por imagem , Implante de Prótese de Valva Cardíaca , Tomografia Computadorizada por Raios X , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/diagnóstico por imagem , Adulto , Idoso , Valva Aórtica/anatomia & histologia , Valva Aórtica/diagnóstico por imagem , Doença da Válvula Aórtica Bicúspide , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Tamanho do Órgão , Reoperação , Adulto Jovem
20.
JACC Cardiovasc Imaging ; 12(3): 458-468, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30846121

RESUMO

An appreciation of the complex and variable anatomy of the tricuspid valve is essential to unraveling the pathophysiology of tricuspid regurgitation. A greater appreciation of normal and abnormal anatomy is important as new methods of treating the tricuspid regurgitation are developed. This review of tricuspid valve and right heart anatomy is followed by a discussion of the possible pathophysiology of secondary (functional) tricuspid regurgitation.


Assuntos
Hemodinâmica , Insuficiência da Valva Tricúspide/fisiopatologia , Valva Tricúspide/anatomia & histologia , Valva Tricúspide/fisiologia , Função Ventricular Direita , Humanos , Fatores de Risco , Valva Tricúspide/diagnóstico por imagem , Insuficiência da Valva Tricúspide/diagnóstico por imagem , Insuficiência da Valva Tricúspide/etiologia
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